4G7N
The Structure of the Plk4 Cryptic Polo Box Reveals Two Tandem Polo Boxes Required for Centriole Duplication
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Serine/threonine-protein kinase PLK4 | polymer | 225 | 25710.5 | 2 | UniProt (O97143) Pfam (PF18190) Pfam (PF18409) In PDB | Drosophila melanogaster (Fruit fly) | Polo-like kinase 4, PLK-4, Serine/threonine-protein kinase SAK |
| 2 | A, B | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 3 | water | water | 18.0 | 184 | Chemie (HOH) |
Sequence modifications
A, B: 382 - 602 (UniProt: O97143)
| PDB | External Database | Details |
|---|---|---|
| Gly 378 | - | EXPRESSION TAG |
| Ser 379 | - | EXPRESSION TAG |
| His 380 | - | EXPRESSION TAG |
| Met 381 | - | EXPRESSION TAG |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 51421.0 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 576.4 | |
| All* | Total formula weight | 51997.4 |
