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4G7N

The Structure of the Plk4 Cryptic Polo Box Reveals Two Tandem Polo Boxes Required for Centriole Duplication

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Serine/threonine-protein kinase PLK4polymer22525710.52UniProt (O97143)
Pfam (PF18190)
Pfam (PF18409)
Drosophila melanogaster (Fruit fly)Polo-like kinase 4, PLK-4, Serine/threonine-protein kinase SAK
2C, D, E, F, G...
(A, B)
SULFATE IONnon-polymer96.16Chemie (SO4)
3I, J
(A, B)
waterwater18.0184Chemie (HOH)
Sequence modifications
A, B: 382 - 602 (UniProt: O97143)
PDBExternal DatabaseDetails
Gly 378-expression tag
Ser 379-expression tag
His 380-expression tag
Met 381-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight51421.0
Non-Polymers*Number of molecules6
Total formula weight576.4
All*Total formula weight51997.4
*Water molecules are not included.

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PDB entries from 2024-11-06

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