4G56
Crystal Structure of full length PRMT5/MEP50 complexes from Xenopus laevis
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | Hsl7 protein | polymer | 657 | 75713.5 | 2 | UniProt (Q6NUA1) Pfam (PF17285) Pfam (PF05185) Pfam (PF17286) In PDB | Xenopus laevis (clawed frog common platanna platanna) | Methyltransferase Hsl7 |
2 | B, D | MGC81050 protein | polymer | 357 | 38872.7 | 2 | UniProt (Q6NUD0) Pfam (PF00400) In PDB | Xenopus laevis (clawed frog common platanna platanna) | |
3 | A, C | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 2 | Chemie (SAH) | |||
4 | water | water | 18.0 | 9 | Chemie (HOH) |
Sequence modifications
A, C: 2 - 633 (UniProt: Q6NUA1)
B, D: 2 - 333 (UniProt: Q6NUD0)
PDB | External Database | Details |
---|---|---|
Mse -23 | - | EXPRESSION TAG |
His -22 | - | EXPRESSION TAG |
His -21 | - | EXPRESSION TAG |
His -20 | - | EXPRESSION TAG |
His -19 | - | EXPRESSION TAG |
His -18 | - | EXPRESSION TAG |
His -17 | - | EXPRESSION TAG |
Ser -16 | - | EXPRESSION TAG |
Ser -15 | - | EXPRESSION TAG |
Gly -14 | - | EXPRESSION TAG |
Val -13 | - | EXPRESSION TAG |
Asp -12 | - | EXPRESSION TAG |
Leu -11 | - | EXPRESSION TAG |
Gly -10 | - | EXPRESSION TAG |
Thr -9 | - | EXPRESSION TAG |
Glu -8 | - | EXPRESSION TAG |
Asn -7 | - | EXPRESSION TAG |
Leu -6 | - | EXPRESSION TAG |
Tyr -5 | - | EXPRESSION TAG |
Phe -4 | - | EXPRESSION TAG |
Gln -3 | - | EXPRESSION TAG |
Ser -2 | - | EXPRESSION TAG |
Asn -1 | - | EXPRESSION TAG |
Gly 0 | - | EXPRESSION TAG |
Ser 1 | - | EXPRESSION TAG |
PDB | External Database | Details |
---|---|---|
Mse -23 | - | EXPRESSION TAG |
His -22 | - | EXPRESSION TAG |
His -21 | - | EXPRESSION TAG |
His -20 | - | EXPRESSION TAG |
His -19 | - | EXPRESSION TAG |
His -18 | - | EXPRESSION TAG |
His -17 | - | EXPRESSION TAG |
Ser -16 | - | EXPRESSION TAG |
Ser -15 | - | EXPRESSION TAG |
Gly -14 | - | EXPRESSION TAG |
Val -13 | - | EXPRESSION TAG |
Asp -12 | - | EXPRESSION TAG |
Leu -11 | - | EXPRESSION TAG |
Gly -10 | - | EXPRESSION TAG |
Thr -9 | - | EXPRESSION TAG |
Glu -8 | - | EXPRESSION TAG |
Asn -7 | - | EXPRESSION TAG |
Leu -6 | - | EXPRESSION TAG |
Tyr -5 | - | EXPRESSION TAG |
Phe -4 | - | EXPRESSION TAG |
Gln -3 | - | EXPRESSION TAG |
Ser -2 | - | EXPRESSION TAG |
Asn -1 | - | EXPRESSION TAG |
Gly 0 | - | EXPRESSION TAG |
Ser 1 | - | EXPRESSION TAG |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 229172.4 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 768.8 | |
All* | Total formula weight | 229941.2 |