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4G3Y

Crystal structure of TNF-alpha in complex with Infliximab Fab fragment

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(L)
infliximab Fab Lpolymer21423460.91Homo sapiens (human)
2B
(H)
infliximab Fab Hpolymer22624356.21Homo sapiens (human)
3C
(C)
Tumor necrosis factorpolymer15717370.71UniProt (P01375)
Pfam (PF00229)
Homo sapiens (human)TNF-alpha
4D, E, F
(L, H, C)
waterwater18.0134Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight65187.7
All*Total formula weight65187.7
*Water molecules are not included.

246704

PDB entries from 2025-12-24

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