4G1N
PKM2 in complex with an activator
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Pyruvate kinase isozymes M1/M2 | polymer | 518 | 56657.3 | 4 | UniProt (P14618) Pfam (PF00224) Pfam (PF02887) In PDB | Homo sapiens (human) | Cytosolic thyroid hormone-binding protein, CTHBP, Opa-interacting protein 3, OIP-3, Pyruvate kinase 2/3, Pyruvate kinase muscle isozyme, Thyroid hormone-binding protein 1, THBP1, Tumor M2-PK, p58 |
| 2 | A, B, C, D | OXALATE ION | non-polymer | 88.0 | 4 | Chemie (OXL) | |||
| 3 | A, B, C, D | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 4 | A, D | N-(4-{[4-(pyrazin-2-yl)piperazin-1-yl]carbonyl}phenyl)quinoline-8-sulfonamide | non-polymer | 474.5 | 2 | Chemie (NZT) | |||
| 5 | water | water | 18.0 | 222 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 226629.2 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1398.4 | |
| All* | Total formula weight | 228027.5 |
