4G1E
Crystal structure of integrin alpha V beta 3 with coil-coiled tag.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Integrin alpha-V | polymer | 998 | 110396.2 | 1 | UniProt (P06756) Pfam (PF01839) Pfam (PF08441) Pfam (PF20805) Pfam (PF20806) | Homo sapiens (human) | Vitronectin receptor subunit alpha, Integrin alpha-V heavy chain, Integrin alpha-V light chain |
| 2 | B (B) | Integrin beta-3 | polymer | 738 | 81884.4 | 1 | UniProt (P05106) Pfam (PF07974) Pfam (PF07965) Pfam (PF17205) Pfam (PF00362) Pfam (PF18372) | Homo sapiens (human) | Platelet membrane glycoprotein IIIa, GPIIIa |
| 3 | C, M, O (C, M, O) | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 3 | In PDB GlyTouCan (G22573RC) | |||
| 4 | D, H, N (D, H, N) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G15407YE) | |||
| 5 | E (E) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1397.2 | 1 | In PDB GlyTouCan (G86582QF) | |||
| 6 | F (F) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
| 7 | G, J, K, L (G, J, K, L) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 4 | In PDB GlyTouCan (G42666HT) | |||
| 8 | I (I) | alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 1 | In PDB GlyTouCan (G09724ZC) | |||
| 9 | EA, P, Q, R, S... (B, A) | CALCIUM ION | non-polymer | 40.1 | 6 | Chemie (CA) | |||
| 10 | U, V (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 11 | FA, GA, HA, W, X... (B, A) | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 12 | AA, BA, CA, IA, JA... (A, B) | CHLORIDE ION | non-polymer | 35.5 | 7 | Chemie (CL) | |||
| 13 | DA (A) | NICKEL (II) ION | non-polymer | 58.7 | 1 | Chemie (NI) | |||
| 14 | LA, MA (A, B) | water | water | 18.0 | 99 | Chemie (HOH) |
Sequence modifications
A: 1 - 959 (UniProt: P06756)
B: 1 - 691 (UniProt: P05106)
| PDB | External Database | Details |
|---|---|---|
| Met 960 | - | expression tag |
| Gly 961 | - | expression tag |
| Ser 962 | - | expression tag |
| Gly 963 | - | expression tag |
| Gly 964 | - | expression tag |
| Glu 965 | - | expression tag |
| Asn 966 | - | expression tag |
| Ala 967 | - | expression tag |
| Gln 968 | - | expression tag |
| Cys 969 | - | expression tag |
| Glu 970 | - | expression tag |
| Lys 971 | - | expression tag |
| Glu 972 | - | expression tag |
| Leu 973 | - | expression tag |
| Gln 974 | - | expression tag |
| Ala 975 | - | expression tag |
| Leu 976 | - | expression tag |
| Glu 977 | - | expression tag |
| Lys 978 | - | expression tag |
| Glu 979 | - | expression tag |
| Asn 980 | - | expression tag |
| Ala 981 | - | expression tag |
| Gln 982 | - | expression tag |
| Leu 983 | - | expression tag |
| Glu 984 | - | expression tag |
| Trp 985 | - | expression tag |
| Glu 986 | - | expression tag |
| Leu 987 | - | expression tag |
| Gln 988 | - | expression tag |
| Ala 989 | - | expression tag |
| Leu 990 | - | expression tag |
| Glu 991 | - | expression tag |
| Lys 992 | - | expression tag |
| Glu 993 | - | expression tag |
| Leu 994 | - | expression tag |
| Gln 995 | - | expression tag |
| Ala 996 | - | expression tag |
| Leu 997 | - | expression tag |
| Cys 998 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Glu 692 | - | expression tag |
| Ser 693 | - | expression tag |
| Met 694 | - | expression tag |
| Glu 695 | - | expression tag |
| Asn 696 | - | expression tag |
| Leu 697 | - | expression tag |
| Tyr 698 | - | expression tag |
| Phe 699 | - | expression tag |
| Gln 700 | - | expression tag |
| Ser 701 | - | expression tag |
| Gly 702 | - | expression tag |
| Gly 703 | - | expression tag |
| Lys 704 | - | expression tag |
| Asn 705 | - | expression tag |
| Ala 706 | - | expression tag |
| Gln 707 | - | expression tag |
| Cys 708 | - | expression tag |
| Lys 709 | - | expression tag |
| Lys 710 | - | expression tag |
| Lys 711 | - | expression tag |
| Leu 712 | - | expression tag |
| Gln 713 | - | expression tag |
| Ala 714 | - | expression tag |
| Leu 715 | - | expression tag |
| Lys 716 | - | expression tag |
| Lys 717 | - | expression tag |
| Lys 718 | - | expression tag |
| Asn 719 | - | expression tag |
| Ala 720 | - | expression tag |
| Gln 721 | - | expression tag |
| Leu 722 | - | expression tag |
| Lys 723 | - | expression tag |
| Trp 724 | - | expression tag |
| Lys 725 | - | expression tag |
| Leu 726 | - | expression tag |
| Gln 727 | - | expression tag |
| Ala 728 | - | expression tag |
| Leu 729 | - | expression tag |
| Cys 730 | - | expression tag |
| Thr 731 | - | expression tag |
| Gly 732 | - | expression tag |
| His 733 | - | expression tag |
| His 734 | - | expression tag |
| His 735 | - | expression tag |
| His 736 | - | expression tag |
| His 737 | - | expression tag |
| His 738 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 192280.6 | |
| Branched | Number of molecules | 13 |
| Total formula weight | 8922.2 | |
| Non-Polymers* | Number of molecules | 22 |
| Total formula weight | 1566.1 | |
| All* | Total formula weight | 202768.9 |
