4G0N
Crystal Structure of wt H-Ras-GppNHp bound to the RBD of Raf Kinase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | GTPase HRas | polymer | 166 | 18875.2 | 1 | UniProt (P01112) Pfam (PF00071) | Homo sapiens (human) | H-Ras-1, Ha-Ras, Transforming protein p21, c-H-ras, p21ras, GTPase HRas, N-terminally processed |
| 2 | B (B) | RAF proto-oncogene serine/threonine-protein kinase | polymer | 78 | 8890.4 | 1 | UniProt (P04049) Pfam (PF02196) | Homo sapiens (human) | Proto-oncogene c-RAF, cRaf, Raf-1 |
| 3 | C (A) | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 1 | Chemie (GNP) | |||
| 4 | D, F (A) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 5 | E (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 6 | G (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 7 | H (A) | (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL | non-polymer | 154.3 | 1 | Chemie (DTU) | |||
| 8 | I, J (A, B) | water | water | 18.0 | 82 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27765.6 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 840.0 | |
| All* | Total formula weight | 28605.5 |
