4G0D
Human collagenase 3 (MMP-13) full form with peptides from pro-domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Collagenase 3 | polymer | 368 | 42284.6 | 4 | UniProt (P45452) Pfam (PF00413) Pfam (PF00045) | Homo sapiens (human) | Matrix metalloproteinase-13, MMP-13 |
| 2 | E, F, G, H (W, X, Y, Z) | Collagenase 3, pro-domain peptide | polymer | 26 | 3109.2 | 4 | UniProt (P45452) Pfam (PF01471) | Homo sapiens (human) | Matrix metalloproteinase-13, MMP-13 |
| 3 | CA, DA, I, J, UB... (B, A, D, C) | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
| 4 | AB, AC, BB, CB, EA... (C, D, B, A) | CALCIUM ION | non-polymer | 40.1 | 23 | Chemie (CA) | |||
| 5 | BC, CC, DB, JA, LA... (D, C, B, Y, A...) | CHLORIDE ION | non-polymer | 35.5 | 8 | Chemie (CL) | |||
| 6 | AA, DC, EC, FC, GB... (A, D, C, B) | S-1,2-PROPANEDIOL | non-polymer | 76.1 | 38 | Chemie (PGO) | |||
| 7 | BA, MA, OA, PA (A, B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 4 | Chemie (PEG) | |||
| 8 | HB, IB, NA, RA, RB (C, B) | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 9 | QC, RC, SC, TC, UC... (A, B, C, D, W...) | water | water | 18.0 | 896 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 104 - 471 (UniProt: P45452)
| PDB | External Database | Details |
|---|---|---|
| Ala 223 | Glu 223 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 181575.3 | |
| Non-Polymers* | Number of molecules | 86 |
| Total formula weight | 5505.2 | |
| All* | Total formula weight | 187080.5 |
