4G0C
Neutron structure of acetazolamide-bound human carbonic anhydrase II reveal molecular details of drug binding.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Carbonic anhydrase 2 | polymer | 257 | 28932.6 | 1 | UniProt (P00918) Pfam (PF00194) In PDB | Homo sapiens (human) | Carbonate dehydratase II, Carbonic anhydrase C, CAC, Carbonic anhydrase II, CA-II |
| 2 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | A | 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE | non-polymer | 222.2 | 1 | Chemie (AZM) | |||
| 4 | water | water | 18.0 | 144 | Chemie (DOD) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28932.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 287.7 | |
| All* | Total formula weight | 29220.3 |
