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4FWJ

Native structure of LSD2/AOF1/KDM1b in spacegroup of I222 at 2.9A

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Lysine-specific histone demethylase 1Bpolymer79689341.02UniProt (Q8NB78)
Pfam (PF07496)
Pfam (PF04433)
Pfam (PF01593)
Homo sapiens (human)Flavin-containing amine oxidase domain-containing protein 1, Lysine-specific histone demethylase 2
2C, D, E, H, I...
(A, B)
ZINC IONnon-polymer65.46Chemie (ZN)
3F, K
(A, B)
FLAVIN-ADENINE DINUCLEOTIDEnon-polymer785.52Chemie (FAD)
4G
(A)
POTASSIUM IONnon-polymer39.11Chemie (K)
5L
(B)
PHOSPHATE IONnon-polymer95.01Chemie (PO4)
6M, N
(A, B)
waterwater18.0464Chemie (HOH)
Sequence modifications
A, B: 30 - 822 (UniProt: Q8NB78)
PDBExternal DatabaseDetails
Gly 27-expression tag
His 28-expression tag
Met 29-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight178682.0
Non-Polymers*Number of molecules10
Total formula weight2097.6
All*Total formula weight180779.6
*Water molecules are not included.

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PDB entries from 2025-07-23

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