4FVL
Human collagenase 3 (MMP-13) full form with peptides from pro-domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Collagenase 3 | polymer | 368 | 42284.6 | 2 | UniProt (P45452) Pfam (PF00413) Pfam (PF00045) In PDB | Homo sapiens (human) | Matrix metalloproteinase-13, MMP-13 |
| 2 | C, D | Collagenase 3, pro-domain peptide | polymer | 20 | 2520.7 | 2 | UniProt (P45452) Pfam (PF01471) In PDB | Homo sapiens (human) | Matrix metalloproteinase-13, MMP-13 |
| 3 | A, B | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 4 | A, B | CALCIUM ION | non-polymer | 40.1 | 10 | Chemie (CA) | |||
| 5 | A, B | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 6 | A, B | GLYCEROL | non-polymer | 92.1 | 10 | Chemie (GOL) | |||
| 7 | A, B, C | S-1,2-PROPANEDIOL | non-polymer | 76.1 | 28 | Chemie (PGO) | |||
| 8 | A, B, D | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 9 | Chemie (PEG) | |||
| 9 | water | water | 18.0 | 234 | Chemie (HOH) |
Sequence modifications
A, B: 104 - 471 (UniProt: P45452)
| PDB | External Database | Details |
|---|---|---|
| Ala 223 | Glu 223 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 89610.7 | |
| Non-Polymers* | Number of molecules | 64 |
| Total formula weight | 4775.4 | |
| All* | Total formula weight | 94386.1 |
