4FU6

Crystal structure of the PSIP1 PWWP domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	PC4 and SFRS1-interacting protein	polymer	153	17518.4	1	UniProt (O75475) Pfam (PF00855)	Homo sapiens (human)	CLL-associated antigen KW-7, Dense fine speckles 70 kDa protein, DFS 70, Lens epithelium-derived growth factor, Transcriptional coactivator p75/p52
2	B, C, D (A)	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)
3	E (A)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
4	F, G, H, I, J (A)	UNKNOWN ATOM OR ION	non-polymer			5	Chemie (UNX)
5	K (A)	water	water		18.0	30	Chemie (HOH)

Sequence modifications

A: 1 - 135 (UniProt: O75475)

PDB	External Database	Details
Met -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
Ser -10	-	expression tag
Ser -9	-	expression tag
Gly -8	-	expression tag
Arg -7	-	expression tag
Glu -6	-	expression tag
Asn -5	-	expression tag
Leu -4	-	expression tag
Tyr -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Gly 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	17518.4
Non-Polymers*	Number of molecules	9
	Total formula weight	380.3
All*	Total formula weight	17898.7

*Water molecules are not included.