4FU4
Human collagenase 3 (MMP-13) with peptide from pro-domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Collagenase 3 | polymer | 368 | 42284.6 | 2 | UniProt (P45452) Pfam (PF00413) Pfam (PF00045) | Homo sapiens (human) | Matrix metalloproteinase-13, MMP-13 |
| 2 | C, D (C, D) | Collagenase 3, pro-domain peptide | polymer | 26 | 3109.2 | 2 | UniProt (P45452) Pfam (PF01471) | Homo sapiens (human) | Matrix metalloproteinase-13, MMP-13 |
| 3 | E, F, W, X (A, B) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 4 | AA, BA, G, H, I... (B, A) | CALCIUM ION | non-polymer | 40.1 | 8 | Chemie (CA) | |||
| 5 | CA, K, QA, SA (B, A, C, D) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 6 | DA, EA, FA, GA, HA... (B, A, C, D) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 26 | Chemie (EDO) | |||
| 7 | UA, VA, WA, XA (A, B, C, D) | water | water | 18.0 | 104 | Chemie (HOH) |
Sequence modifications
A, B: 104 - 471 (UniProt: P45452)
| PDB | External Database | Details |
|---|---|---|
| Ala 223 | Glu 223 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 90787.7 | |
| Non-Polymers* | Number of molecules | 42 |
| Total formula weight | 2337.8 | |
| All* | Total formula weight | 93125.5 |
