4FTO
Crystal Structure of the CHK1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Serine/threonine-protein kinase Chk1 | polymer | 279 | 32154.0 | 1 | UniProt (O14757) Pfam (PF00069) In PDB | Homo sapiens (human) | CHK1 checkpoint homolog, Cell cycle checkpoint kinase, Checkpoint kinase-1 |
| 2 | A | 4-{7-methoxy-6-[3-(morpholin-4-yl)propoxy]-1,4-dihydroindeno[1,2-c]pyrazol-3-yl}benzonitrile | non-polymer | 430.5 | 1 | Chemie (3HK) | |||
| 3 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | A | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | A | ISOPROPYL ALCOHOL | non-polymer | 60.1 | 1 | Chemie (IPA) | |||
| 6 | water | water | 18.0 | 145 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32154.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 770.8 | |
| All* | Total formula weight | 32924.9 |
