4FTI
Crystal Structure of the CHK1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein kinase Chk1 | polymer | 279 | 32154.0 | 1 | UniProt (O14757) Pfam (PF00069) | Homo sapiens (human) | CHK1 checkpoint homolog, Cell cycle checkpoint kinase, Checkpoint kinase-1 |
| 2 | B (A) | methyl 5-(6-{[(cis-4-hydroxycyclohexyl)amino]methyl}-2,4-dihydroindeno[1,2-c]pyrazol-3-yl)furan-2-carboxylate | non-polymer | 407.5 | 1 | Chemie (H7K) | |||
| 3 | C (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | D (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | E (A) | ISOPROPYL ALCOHOL | non-polymer | 60.1 | 1 | Chemie (IPA) | |||
| 6 | F (A) | water | water | 18.0 | 154 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32154.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 655.7 | |
| All* | Total formula weight | 32809.8 |
