4FTG
The crystal structure of an AHNAK peptide in complex with the S100A10/AnxA2 heterotetramer
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Protein S100-A10 | polymer | 96 | 11088.9 | 2 | UniProt (P60903) Pfam (PF01023) | Homo sapiens (human) | Calpactin I light chain, Calpactin-1 light chain, Cellular ligand of annexin II, S100 calcium-binding protein A10, p10 protein, p11 |
| 2 | C, D (C, D) | Annexin A2 | polymer | 17 | 1653.9 | 2 | UniProt (P07355) | Homo sapiens | Annexin II, Annexin-2, Calpactin I heavy chain, Calpactin-1 heavy chain, Chromobindin-8, Lipocortin II, Placental anticoagulant protein IV, PAP-IV, Protein I, p36 |
| 3 | E (E) | Neuroblast differentiation-associated protein AHNAK | polymer | 22 | 2340.9 | 1 | UniProt (Q09666) | Homo sapiens | Desmoyokin |
| 4 | F, G, H (A, B, E) | ISOPROPYL ALCOHOL | non-polymer | 60.1 | 3 | Chemie (IPA) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 8 | Chemie (HOH) |
Sequence modifications
C, D: 2 - 16 (UniProt: P07355)
E: 1 - 20 (UniProt: Q09666)
| PDB | External Database | Details |
|---|---|---|
| Ace 1 | - | acetylation |
| Ser 9 | Cys 9 | engineered mutation |
| Nh2 17 | - | amidation |
| PDB | External Database | Details |
|---|---|---|
| Ace 0 | - | acetylation |
| Nh2 21 | - | amidation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 27826.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 180.3 | |
| All* | Total formula weight | 28006.7 |
