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4FTC

Crystal Structure of the CHK1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Serine/threonine-protein kinase Chk1polymer27932170.01UniProt (O14757)
Pfam (PF00069)
Homo sapiens (human)CHK1 checkpoint homolog, Cell cycle checkpoint kinase, Checkpoint kinase-1
2B
(A)
1-(5-cyanopyrazin-2-yl)-3-(5-phenyl-1H-pyrazol-3-yl)ureanon-polymer305.31Chemie (H6K)
3C
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
4D
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
5E, F
(A)
ISOPROPYL ALCOHOLnon-polymer60.12Chemie (IPA)
6G
(A)
waterwater18.0184Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight32170.0
Non-Polymers*Number of molecules5
Total formula weight613.6
All*Total formula weight32783.7
*Water molecules are not included.

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PDB entries from 2025-06-18

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