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4FSZ

Crystal Structure of the CHK1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Serine/threonine-protein kinase Chk1polymer27932186.01UniProt (O14757)
Pfam (PF00069)
Homo sapiens (human)CHK1 checkpoint homolog, Cell cycle checkpoint kinase, Checkpoint kinase-1
2B
(A)
(3-chloro-11-oxo-10,11-dihydro-5H-dibenzo[b,e][1,4]diazepin-8-yl)acetic acidnon-polymer302.71Chemie (HK8)
3C
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
4D, E
(A)
ISOPROPYL ALCOHOLnon-polymer60.12Chemie (IPA)
5F
(A)
waterwater18.0196Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight32186.0
Non-Polymers*Number of molecules4
Total formula weight519.0
All*Total formula weight32705.0
*Water molecules are not included.

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PDB entries from 2025-07-30

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