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4FSU

Crystal Structure of the CHK1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Serine/threonine-protein kinase Chk1polymer27932062.01UniProt (O14757)
Pfam (PF00069)
Homo sapiens (human)CHK1 checkpoint homolog, Cell cycle checkpoint kinase, Checkpoint kinase-1
2B
(A)
4-[6-(1H-imidazol-1-ylmethyl)-7-methoxy-2,4-dihydroindeno[1,2-c]pyrazol-3-yl]benzonitrilenon-polymer367.41Chemie (HK5)
3C
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
4D
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
5E
(A)
ISOPROPYL ALCOHOLnon-polymer60.11Chemie (IPA)
6F
(A)
waterwater18.0165Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight32062.0
Non-Polymers*Number of molecules4
Total formula weight615.7
All*Total formula weight32677.6
*Water molecules are not included.

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PDB entries from 2025-06-18

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