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4FST

Crystal Structure of the CHK1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Serine/threonine-protein kinase Chk1polymer26931084.71UniProt (O14757)
Pfam (PF00069)
Homo sapiens (human)CHK1 checkpoint homolog, Cell cycle checkpoint kinase, Checkpoint kinase-1
2B
(A)
4-[(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]pyrazol-3-yl)ethynyl]-2-methoxyphenolnon-polymer362.41Chemie (HK4)
3C
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
4D, E
(A)
GLYCEROLnon-polymer92.12Chemie (GOL)
5F, G
(A)
ISOPROPYL ALCOHOLnon-polymer60.12Chemie (IPA)
6H
(A)
waterwater18.0226Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight31084.7
Non-Polymers*Number of molecules6
Total formula weight762.8
All*Total formula weight31847.6
*Water molecules are not included.

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PDB entries from 2025-06-18

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