4FSN
Crystal Structure of the CHK1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Serine/threonine-protein kinase Chk1 | polymer | 278 | 32054.9 | 1 | UniProt (O14757) Pfam (PF00069) In PDB | Homo sapiens (human) | CHK1 checkpoint homolog, Cell cycle checkpoint kinase, Checkpoint kinase-1 |
| 2 | A | 4-(6-{[(4-METHYLCYCLOHEXYL)AMINO]METHYL}-1,4-DIHYDROINDENO[1,2-C]PYRAZOL-3-YL)BENZOIC ACID | non-polymer | 401.5 | 1 | Chemie (A58) | |||
| 3 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | A | ISOPROPYL ALCOHOL | non-polymer | 60.1 | 1 | Chemie (IPA) | |||
| 5 | water | water | 18.0 | 190 | Chemie (HOH) |
Sequence modifications
A: 3 - 280 (UniProt: O14757)
| PDB | External Database | Details |
|---|---|---|
| - | Val 5 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32054.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 557.7 | |
| All* | Total formula weight | 32612.6 |
