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4FSM

Crystal Structure of the CHK1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Serine/threonine-protein kinase Chk1polymer27932154.01UniProt (O14757)
Pfam (PF00069)
Homo sapiens (human)CHK1 checkpoint homolog, Cell cycle checkpoint kinase, Checkpoint kinase-1
2B
(A)
4-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]pyrazol-3-yl)phenolnon-polymer308.31Chemie (HK1)
3C
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
4D
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
5E
(A)
ISOPROPYL ALCOHOLnon-polymer60.11Chemie (IPA)
6F
(A)
waterwater18.0191Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight32154.0
Non-Polymers*Number of molecules4
Total formula weight556.6
All*Total formula weight32710.6
*Water molecules are not included.

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PDB entries from 2025-06-11

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