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4FS2

Base pairing mechanism of N2,3-ethenoguanine with dCTP by human polymerase iota

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(B, C)
DNA (5'-D(*TP*CP*TP*(EFG)P*GP*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*(DOC))-3')polymer185534.62
2C
(A)
DNA polymerase iotapolymer42047027.31UniProt (Q9UNA4)
Pfam (PF00817)
Pfam (PF21999)
Pfam (PF11799)
Homo sapiens (human)Eta2, RAD30 homolog B
3D, G, H
(A)
MAGNESIUM IONnon-polymer24.33Chemie (MG)
4E
(A)
SODIUM IONnon-polymer23.01Chemie (NA)
5F
(A)
2'-DEOXYCYTIDINE-5'-TRIPHOSPHATEnon-polymer467.21Chemie (DCP)
6I, J, K
(B, C, A)
waterwater18.0179Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight58096.5
Non-Polymers*Number of molecules5
Total formula weight563.1
All*Total formula weight58659.5
*Water molecules are not included.

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PDB entries from 2025-06-11

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