4FRR

X-ray structure of Acetylcholine binding protein from Aplysia californica in presence of 3-((S)-azetidin-2-ylmethoxy)-5-((1S,2R)-2-(2-methoxyethyl)cyclopropyl)pyridine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Soluble acetylcholine receptor	polymer	232	26122.3	10	UniProt (Q8WSF8) Pfam (PF02931)	Aplysia californica (California sea hare)
2	CA, IA, K, NA, T... (F, H, A, J, C...)	3-[(2S)-azetidin-2-ylmethoxy]-5-[(1S,2R)-2-(2-methoxyethyl)cyclopropyl]pyridine	non-polymer		262.3	6	Chemie (0VC)
3	AA, BA, DA, EA, FA... (E, F, G, H, I...)	GLYCEROL	non-polymer		92.1	26	Chemie (GOL)
4	QA, RA, SA, TA, UA... (A, B, C, D, E...)	water	water		18.0	822	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H, I, J: 1 - 208 (UniProt: Q8WSF8)

PDB	External Database	Details
Met -23	-	expression tag
Ser -22	-	expression tag
Ala -21	-	expression tag
Leu -20	-	expression tag
Leu -19	-	expression tag
Ile -18	-	expression tag
Leu -17	-	expression tag
Ala -16	-	expression tag
Leu -15	-	expression tag
Val -14	-	expression tag
Gly -13	-	expression tag
Ala -12	-	expression tag
Ala -11	-	expression tag
Val -10	-	expression tag
Ala -9	-	expression tag
Asp -8	-	expression tag
Tyr -7	-	expression tag
Lys -6	-	expression tag
Asp -5	-	expression tag
Asp -4	-	expression tag
Asp -3	-	expression tag
Asp -2	-	expression tag
Lys -1	-	expression tag
Leu 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	261222.6
Non-Polymers*	Number of molecules	32
	Total formula weight	3968.5
All*	Total formula weight	265191.1

*Water molecules are not included.