4FQZ

Crystal structure of a protease-resistant mutant form of human galectin-8

Replaces:  3NAJ

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Galectin-8	polymer	291	33110.1	1	UniProt (O00214) Pfam (PF00337) In PDB	Homo sapiens (human)	Gal-8, Po66 carbohydrate-binding protein, Po66-CBP, Prostate carcinoma tumor antigen 1, PCTA-1
2	B	beta-D-galactopyranose-(1-4)-beta-D-glucopyranose	branched		342.3	1	In PDB BIRD (PRD_900004) GlyTouCan (G84224TW)		beta-lactose
3	A	1,2-ETHANEDIOL	non-polymer		62.1	10	Chemie (EDO)
4		water	water		18.0	43	Chemie (HOH)

Sequence modifications

A: 1 - 155 (UniProt: O00214)
A: 184 - 317 (UniProt: O00214)

PDB	External Database	Details
His 156	-	linker
Met 157	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	33110.1
Branched	Number of molecules	1
	Total formula weight	342.3
Non-Polymers*	Number of molecules	10
	Total formula weight	620.7
All*	Total formula weight	34073.1

*Water molecules are not included.