4FQS

Crystal Structure of Mycobacterium tuberculosis ThyA in complex with UMP and Pemetrexed

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Thymidylate synthase	polymer	263	29884.8	2	UniProt (P67044) Pfam (PF00303) UniProt (by SIFTS) (P9WFR9) In PDB	Mycobacterium tuberculosis	TS, TSase
2	A, B	2'-DEOXYURIDINE 5'-MONOPHOSPHATE	non-polymer		308.2	2	Chemie (UMP)
3	A, B	2-{4-[2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-PENTANEDIOIC ACID	non-polymer		427.4	2	Chemie (LYA)
4		water	water		18.0	1032	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	59769.7
Non-Polymers*	Number of molecules	4
	Total formula weight	1471.2
All*	Total formula weight	61240.8

*Water molecules are not included.