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4FQC

Crystal Structure of PGT121 Fab Bound to a complex-type sialylated N-glycan

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(H)
Fab heavy chainpolymer24426343.51Homo sapiens (human)
2B
(L)
Fab light chainpolymer21122603.01Homo sapiens (human)
3C
(A)
N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranosebranched1916.71In PDB
GlyTouCan (G43694RQ)
4D
(H)
TRIS(HYDROXYETHYL)AMINOMETHANEnon-polymer163.21Chemie (TAM)
5E, F
(H, L)
waterwater18.0146Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight48946.4
BranchedNumber of molecules1
Total formula weight1916.7
Non-Polymers*Number of molecules1
Total formula weight163.2
All*Total formula weight51026.4
*Water molecules are not included.

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PDB entries from 2025-06-25

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