4FPA
Crystal Structure of recombinant human Hexokinase type I mutant D413N Glucose 6-Phosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Hexokinase-1 | polymer | 917 | 102624.1 | 2 | UniProt (P19367) Pfam (PF00349) Pfam (PF03727) | Homo sapiens (human) | Brain form hexokinase, Hexokinase type I, HK I |
| 2 | C, E, J, L (A, B) | beta-D-glucopyranose | non-polymer | 180.2 | 4 | Chemie (BGC) | |||
| 3 | D, F, K, M (A, B) | 6-O-phosphono-beta-D-glucopyranose | non-polymer | 260.1 | 4 | Chemie (BG6) | |||
| 4 | G, H, N, O (A, B) | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) | |||
| 5 | I, P (A, B) | CITRIC ACID | non-polymer | 192.1 | 2 | Chemie (CIT) | |||
| 6 | Q, R (A, B) | water | water | 18.0 | 185 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 917 (UniProt: P19367)
| PDB | External Database | Details |
|---|---|---|
| Asn 413 | Asp 413 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 205248.1 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 2237.4 | |
| All* | Total formula weight | 207485.5 |
