4FOG
Crystal Structure of Mtb ThyA in Complex with 5-Fluoro-dUMP and 5-methyltetrahydrofolic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Thymidylate synthase | polymer | 263 | 29884.8 | 4 | UniProt (P67044) Pfam (PF00303) UniProt (by SIFTS) (P9WFR9) | Mycobacterium tuberculosis | TS, TSase |
| 2 | E, G, H, J (A, B, C, D) | 5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE | non-polymer | 326.2 | 4 | Chemie (UFP) | |||
| 3 | F, I, K (A, C, D) | 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID | non-polymer | 459.5 | 3 | Chemie (C2F) | |||
| 4 | L, M, N, O (A, B, C, D) | water | water | 18.0 | 298 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 119539.3 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 2683.1 | |
| All* | Total formula weight | 122222.4 |
