4FO9

Crystal structure of the E3 SUMO Ligase PIAS2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	E3 SUMO-protein ligase PIAS2	polymer	360	40630.0	1	UniProt (O75928) Pfam (PF14324) Pfam (PF02891)	Homo sapiens (human)	Androgen receptor-interacting protein 3, ARIP3, DAB2-interacting protein, DIP, Msx-interacting zinc finger protein, Miz1, PIAS-NY protein, Protein inhibitor of activated STAT x, Protein inhibitor of activated STAT2
2	B (A)	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
3	C, D, E, F, G... (A)	UNKNOWN ATOM OR ION	non-polymer			20	Chemie (UNX)
4	W (A)	water	water		18.0	43	Chemie (HOH)

Sequence modifications

A: 147 - 488 (UniProt: O75928)

PDB	External Database	Details
Met 129	-	expression tag
His 130	-	expression tag
His 131	-	expression tag
His 132	-	expression tag
His 133	-	expression tag
His 134	-	expression tag
His 135	-	expression tag
Ser 136	-	expression tag
Ser 137	-	expression tag
Gly 138	-	expression tag
Arg 139	-	expression tag
Glu 140	-	expression tag
Asn 141	-	expression tag
Leu 142	-	expression tag
Tyr 143	-	expression tag
Phe 144	-	expression tag
Gln 145	-	expression tag
Gly 146	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	40630.0
Non-Polymers*	Number of molecules	21
	Total formula weight	65.4
All*	Total formula weight	40695.4

*Water molecules are not included.