4FMM

Dimeric Sec14 family homolog 3 from Saccharomyces cerevisiae presents some novel features of structure that lead to a surprising "dimer-monomer" state change induced by substrate binding

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Phosphatidylinositol transfer protein PDR16	polymer	360	41988.2	2	UniProt (P53860) Pfam (PF03765) Pfam (PF00650)	Saccharomyces cerevisiae (yeast)	SEC14 homolog 3, PITP, Pleiotropic drug resistance protein 16
2	C, D, E, F, G... (A, B)	GLYCEROL	non-polymer		92.1	9	Chemie (GOL)
3	I, M, N (A, B)	MAGNESIUM ION	non-polymer		24.3	3	Chemie (MG)
4	O, P (A, B)	water	water		18.0	270	Chemie (HOH)

Sequence modifications

A, B: 1 - 351 (UniProt: P53860)

PDB	External Database	Details
Leu 352	-	expression tag
Glu 353	-	expression tag
His 354	-	expression tag
His 355	-	expression tag
His 356	-	expression tag
His 357	-	expression tag
His 358	-	expression tag
His 359	-	expression tag
His 360	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	83976.5
Non-Polymers*	Number of molecules	12
	Total formula weight	901.8
All*	Total formula weight	84878.2

*Water molecules are not included.