4FKK

Crystal structure of porcine aminopeptidase-N complexed with bestatin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Aminopeptidase N	polymer	909	103636.2	1	UniProt (P15145) Pfam (PF17900) Pfam (PF01433) Pfam (PF11838) In PDB	Sus scrofa (pig)	AP-N, pAPN, Alanyl aminopeptidase, Aminopeptidase M, AP-M, Microsomal aminopeptidase, gp130
2	B, C, F	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		627.6	3	In PDB BIRD (PRD_900017) GlyTouCan (G47362BJ)		triacetyl-beta-chitotriose
3	D, E, G, H, I...	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	6	In PDB GlyTouCan (G42666HT)
4	A	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
5	A	2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID	non-polymer		308.4	1	Chemie (BES)
6	A	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
7		water	water		18.0	848	Chemie (HOH)

Sequence modifications

A: 62 - 963 (UniProt: P15145)

PDB	External Database	Details
Asn 82	Phe 82	conflict
Phe 107	Leu 107	conflict
Ser 964	-	expression tag
His 965	-	expression tag
His 966	-	expression tag
His 967	-	expression tag
His 968	-	expression tag
His 969	-	expression tag
His 970	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	103636.2
Branched	Number of molecules	9
	Total formula weight	4429.2
Non-Polymers*	Number of molecules	4
	Total formula weight	816.2
All*	Total formula weight	108881.6

*Water molecules are not included.