4FIC
Kinase domain of cSrc in complex with a hinge region-binding fragment
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Proto-oncogene tyrosine-protein kinase Src | polymer | 286 | 32726.6 | 2 | UniProt (P00523) Pfam (PF07714) | Gallus gallus (bantam chickens) | Proto-oncogene c-Src, pp60c-src, p60-Src |
| 2 | C, D (A, B) | 6-phenyl[1,2,4]triazolo[1,5-a]pyrazin-2-amine | non-polymer | 211.2 | 2 | Chemie (0UL) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 97 | Chemie (HOH) |
Sequence modifications
A, B: 251 - 533 (UniProt: P00523)
| PDB | External Database | Details |
|---|---|---|
| Gly 248 | - | expression tag |
| His 249 | - | expression tag |
| Met 250 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 65453.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 422.4 | |
| All* | Total formula weight | 65875.7 |
