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4FGZ

Crystal Structure of Phosphoethanolamine Methyltransferase from Plasmodium falciparum in Complex with Amodiaquine

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Phosphoethanolamine N-methyltransferasepolymer26631084.12UniProt (Q6T755)
Pfam (PF13649)
UniProt (by SIFTS) (Q8IDQ9)
Plasmodium falciparum
2C, D, G, H
(A, B)
4-[(7-CHLOROQUINOLIN-4-YL)AMINO]-2-[(DIETHYLAMINO)METHYL]PHENOLnon-polymer355.94Chemie (CQA)
3E, I
(A, B)
S-ADENOSYL-L-HOMOCYSTEINEnon-polymer384.42Chemie (SAH)
4F, J
(A, B)
PHOSPHATE IONnon-polymer95.02Chemie (PO4)
5K, L
(A, B)
waterwater18.0191Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight62168.2
Non-Polymers*Number of molecules8
Total formula weight2382.2
All*Total formula weight64550.4
*Water molecules are not included.

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PDB entries from 2025-12-24

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