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4FFX

Structural and Biochemical Characterization of Human Adenylosuccinate Lyase (ADSL) and the R303C ADSL Deficiency Associated Mutation

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, DAdenylosuccinate lyasepolymer48755273.64UniProt (P30566)
Pfam (PF00206)
Pfam (PF10397)
In PDB
Homo sapiens (human)ASL, Adenylosuccinase, ASase
2waterwater18.0214Chemie (HOH)
Sequence modifications
A, B, C, D: 1 - 484 (UniProt: P30566)
PDBExternal DatabaseDetails
Gly -2-expression tag
Ser -1-expression tag
His 0-expression tag
Arg 63Gln 63conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight221094.2
All*Total formula weight221094.2
*Water molecules are not included.

224572

PDB entries from 2024-09-04

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