4FFS
Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Helicobacter pylori with butyl-thio-DADMe-Immucillin-A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | MTA/SAH nucleosidase | polymer | 239 | 26286.3 | 1 | UniProt (Q9ZMY2) Pfam (PF01048) | Helicobacter pylori | 5'-methylthioadenosine nucleosidase, S-adenosylhomocysteine nucleosidase |
| 2 | B (A) | (3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-[(butylsulfanyl)methyl]pyrrolidin-3-ol | non-polymer | 335.5 | 1 | Chemie (BIG) | |||
| 3 | C (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | D (A) | water | water | 18.0 | 229 | Chemie (HOH) |
Sequence modifications
A: 1 - 230 (UniProt: Q9ZMY2)
| PDB | External Database | Details |
|---|---|---|
| Met -8 | - | initiating methionine |
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| Glu -1 | - | expression tag |
| Phe 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 26286.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 370.9 | |
| All* | Total formula weight | 26657.2 |
