4FDJ

The molecular basis of mucopolysaccharidosis IV A, complex with GalNAc

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	N-acetylgalactosamine-6-sulfatase	polymer	502	56301.4	2	UniProt (P34059) Pfam (PF00884) Pfam (PF14707) In PDB	Homo sapiens (human)	GALNS, Chondroitinsulfatase, Chondroitinase, Galactose-6-sulfate sulfatase, N-acetylgalactosamine-6-sulfate sulfatase, GalNAc6S sulfatase
2	A, B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	4	Chemie (NAG)
3	A, B	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
4	A, B	2-acetamido-2-deoxy-beta-D-galactopyranose	non-polymer		221.2	2	Chemie (NGA)
5		water	water		18.0	205	Chemie (HOH)

Sequence modifications

A, B: 27 - 522 (UniProt: P34059)

PDB	External Database	Details
His 523	-	expression tag
His 524	-	expression tag
His 525	-	expression tag
His 526	-	expression tag
His 527	-	expression tag
His 528	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	112602.9
Non-Polymers*	Number of molecules	8
	Total formula weight	1407.4
All*	Total formula weight	114010.3

*Water molecules are not included.