4F8K

Molecular analysis of the interaction between the prostacyclin receptor and the first PDZ domain of PDZK1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Na(+)/H(+) exchange regulatory cofactor NHE-RF3, Prostacyclin receptor	polymer	109	12016.5	2	UniProt (Q9JIL4) UniProt (P43252) Pfam (PF00595)	Mus musculus (mouse)	NHERF-3, CFTR-associated protein of 70 kDa, Na(+)/H(+) exchanger regulatory factor 3, Na/Pi cotransporter C-terminal-associated protein 1, NaPi-Cap1, PDZ domain-containing protein 1, Sodium-hydrogen exchanger regulatory factor 3, Prostaglandin I2 receptor, PGI receptor, PGI2 receptor, Prostanoid IP receptor
2	C, D (A, B)	water	water		18.0	132	Chemie (HOH)

Sequence modifications

A, B: 7 - 106 (UniProt: Q9JIL4)

PDB	External Database	Details
Gly 5	-	expression tag
Ser 6	-	expression tag
Ser 10	Cys 10	engineered mutation

A, B: 107 - 113 (UniProt: P43252)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	24033.1
All*	Total formula weight	24033.1

*Water molecules are not included.