4F4P
SYK in COMPLEX WITH LIGAND LASW836
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tyrosine-protein kinase SYK | polymer | 273 | 31593.4 | 1 | UniProt (P43405) Pfam (PF07714) | Homo sapiens (human) | Spleen tyrosine kinase, p72-Syk |
| 2 | B (A) | N-{6-[3-(piperazin-1-yl)phenyl]pyridin-2-yl}-4-(trifluoromethyl)pyridin-2-amine | non-polymer | 399.4 | 1 | Chemie (0SB) | |||
| 3 | C (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | D (A) | water | water | 18.0 | 21 | Chemie (HOH) |
Sequence modifications
A: 365 - 635 (UniProt: P43405)
| PDB | External Database | Details |
|---|---|---|
| Glu 636 | - | expression tag |
| Gly 637 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 31593.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 495.5 | |
| All* | Total formula weight | 32088.9 |
