4F32

Crystal structure of 3-oxoacyl-[acyl-carrier-protein] synthase II from Burkholderia vietnamiensis in complex with platencin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	3-oxoacyl-[acyl-carrier-protein] synthase 2	polymer	451	46803.8	2	UniProt (A4JL30)	Burkholderia vietnamiensis
2	C (C)	Unknown peptide	polymer	3	273.3	1		Streptomyces platensis
3	D, F (A, B)	2,4-dihydroxy-3-({3-[(2S,4aS,8S,8aR)-8-methyl-3-methylidene-7-oxo-1,3,4,7,8,8a-hexahydro-2H-2,4a-ethanonaphthalen-8-yl]propanoyl}amino)benzoic acid	non-polymer		425.5	2	Chemie (N32) PubChem (11568061) PubChem (11582655) PubChem (44450228) PubChem (44608009) PubChem (177545634) PubChem (16745128) PubChem (50992490) PubChem (51340321) PubChem (133645844) PubChem (59364552) PubChem (73009914) PubChem (89201767) PubChem (89972811) PubChem (101952030) PubChem (102267264) PubChem (124524465) PubChem (132542758) PubChem (132542759) PubChem (138975733) PubChem (163052197)
4	E, G (A, B)	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
5	H, I (A, B)	water	water		18.0	816	Chemie (HOH)

Sequence modifications

A, B: 1 - 430 (UniProt: A4JL30)

PDB	External Database	Details
Met -20	-	expression tag
Ala -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
Met -12	-	expression tag
Gly -11	-	expression tag
Thr -10	-	expression tag
Leu -9	-	expression tag
Glu -8	-	expression tag
Ala -7	-	expression tag
Gln -6	-	expression tag
Thr -5	-	expression tag
Gln -4	-	expression tag
Gly -3	-	expression tag
Pro -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	93881.0
Non-Polymers*	Number of molecules	4
	Total formula weight	975.1
All*	Total formula weight	94856.0

*Water molecules are not included.