4F32
Crystal structure of 3-oxoacyl-[acyl-carrier-protein] synthase II from Burkholderia vietnamiensis in complex with platencin
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004315 | molecular_function | 3-oxoacyl-[acyl-carrier-protein] synthase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0006631 | biological_process | fatty acid metabolic process |
| A | 0006633 | biological_process | fatty acid biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| A | 0030497 | biological_process | fatty acid elongation |
| B | 0004315 | molecular_function | 3-oxoacyl-[acyl-carrier-protein] synthase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0006629 | biological_process | lipid metabolic process |
| B | 0006631 | biological_process | fatty acid metabolic process |
| B | 0006633 | biological_process | fatty acid biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016746 | molecular_function | acyltransferase activity |
| B | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| B | 0030497 | biological_process | fatty acid elongation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE N32 A 501 |
| Chain | Residue |
| A | CSU172 |
| A | THR317 |
| A | PRO318 |
| A | VAL319 |
| A | GLY320 |
| A | HIS349 |
| A | PHE407 |
| A | GLY408 |
| A | HOH674 |
| A | HOH730 |
| A | ALA214 |
| A | ARG215 |
| A | HIS278 |
| A | THR280 |
| A | ALA281 |
| A | GLY282 |
| A | HIS313 |
| A | THR315 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 502 |
| Chain | Residue |
| A | GLU190 |
| B | GLY180 |
| B | ARG184 |
| site_id | AC3 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE N32 B 500 |
| Chain | Residue |
| B | CSU172 |
| B | ALA214 |
| B | ARG215 |
| B | PHE239 |
| B | HIS278 |
| B | THR280 |
| B | ALA281 |
| B | GLY282 |
| B | HIS313 |
| B | THR315 |
| B | THR317 |
| B | PRO318 |
| B | VAL319 |
| B | GLY320 |
| B | HIS349 |
| B | PHE407 |
| B | GLY408 |
| B | HOH652 |
| B | HOH655 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 501 |
| Chain | Residue |
| A | MET183 |
| A | ARG184 |
| A | ARG187 |
| B | GLU190 |
| B | HOH920 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 27 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. IGYGTTADAYhMtagpddgsgam.......RAMK |
| Chain | Residue | Details |
| A | ILE268-LYS294 |
| site_id | PS00606 |
| Number of Residues | 17 |
| Details | KS3_1 Ketosynthase family 3 (KS3) active site signature. GPLgcPVtACAASvqAI |
| Chain | Residue | Details |
| A | GLY163-ILE179 |
