4F2T
Modulation of S.aureus Phosphatidylinositol-Specific Phospholipase C Membrane Binding.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 1-phosphatidylinositol phosphodiesterase | polymer | 310 | 35166.0 | 1 | UniProt (P45723) Pfam (PF00388) | Staphylococcus aureus subsp. aureus | Phosphatidylinositol diacylglycerol-lyase, Phosphatidylinositol-specific phospholipase C, PI-PLC |
| 2 | B, C, D (A) | ACETATE ION | non-polymer | 59.0 | 3 | Chemie (ACT) | |||
| 3 | E (A) | water | water | 18.0 | 103 | Chemie (HOH) |
Sequence modifications
A: 1 - 302 (UniProt: P45723)
| PDB | External Database | Details |
|---|---|---|
| Ser 253 | Tyr 263 | engineered mutation |
| Leu 303 | - | expression tag |
| Glu 304 | - | expression tag |
| His 305 | - | expression tag |
| His 306 | - | expression tag |
| His 307 | - | expression tag |
| His 308 | - | expression tag |
| His 309 | - | expression tag |
| His 310 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 35166.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 177.1 | |
| All* | Total formula weight | 35343.2 |
