4F2T

Modulation of S.aureus Phosphatidylinositol-Specific Phospholipase C Membrane Binding.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006629	biological_process	lipid metabolic process
A	0008081	molecular_function	phosphoric diester hydrolase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ACT A 401

Chain	Residue
A	LYS113
A	ARG166
A	TRP185
A	HOH518
A	HOH599

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ACT A 402

Chain	Residue
A	HIS86
A	LEU37
A	LYS38
A	ASP39
A	LYS42

---

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE ACT A 403

Chain	Residue
A	HIS30
A	HIS80
A	TYR208
A	VAL242
A	ALA243
A	HOH511
A	HOH572

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU00270

Chain	Residue	Details
A	HIS30

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site_id	SWS_FT_FI2
Number of Residues	1
Details	ACT_SITE: Proton donor => ECO:0000255|PROSITE-ProRule:PRU00270

Chain	Residue	Details
A	HIS80

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