4F2M
Crystal structure of a TGEV coronavirus Spike fragment in complex with the TGEV neutralizing monoclonal antibody 1AF10
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | monoclonal antibody 1AF10, heavy chain | polymer | 221 | 23643.4 | 2 | Mus musculus (mouse) | ||
| 2 | B, D (B, D) | monoclonal antibody 1AF10, light chain | polymer | 214 | 23484.8 | 2 | Mus musculus (mouse) | ||
| 3 | E, F (E, F) | Spike protein | polymer | 209 | 23191.0 | 2 | UniProt (Q0PKZ5) Pfam (PF01600) | TGEV virulent Purdue | |
| 4 | G, H, I, J (G, H, I, J) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 4 | In PDB GlyTouCan (G42666HT) | |||
| 5 | K, L (B, D) | ACETIC ACID | non-polymer | 60.1 | 2 | Chemie (ACY) | |||
| 6 | M (F) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 7 | N, O (B, D) | water | water | 18.0 | 2 | Chemie (HOH) |
Sequence modifications
E, F: 481 - 650 (UniProt: Q0PKZ5)
| PDB | External Database | Details |
|---|---|---|
| Tyr 456 | - | expression tag |
| Pro 457 | - | expression tag |
| Tyr 458 | - | expression tag |
| Asp 459 | - | expression tag |
| Val 460 | - | expression tag |
| Pro 461 | - | expression tag |
| Asp 462 | - | expression tag |
| Tyr 463 | - | expression tag |
| Ala 464 | - | expression tag |
| Gly 465 | - | expression tag |
| Ala 466 | - | expression tag |
| Gln 467 | - | expression tag |
| Pro 468 | - | expression tag |
| Ala 469 | - | expression tag |
| Arg 470 | - | expression tag |
| Ser 471 | - | expression tag |
| Pro 472 | - | expression tag |
| Gly 473 | - | expression tag |
| Leu 474 | - | expression tag |
| Val 475 | - | expression tag |
| Pro 476 | - | expression tag |
| Arg 477 | - | expression tag |
| Gly 478 | - | expression tag |
| Ser 479 | - | expression tag |
| Arg 480 | - | expression tag |
| Leu 651 | - | expression tag |
| Val 652 | - | expression tag |
| Pro 653 | - | expression tag |
| Arg 654 | - | expression tag |
| Gly 655 | - | expression tag |
| Ser 656 | - | expression tag |
| Asp 657 | - | expression tag |
| Tyr 658 | - | expression tag |
| Lys 659 | - | expression tag |
| Asp 660 | - | expression tag |
| Asp 661 | - | expression tag |
| Asp 662 | - | expression tag |
| Asp 663 | - | expression tag |
| Lys 664 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 140638.4 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 1697.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 341.3 | |
| All* | Total formula weight | 142677.3 |
