4F1M
Crystal Structure of the G1179S Roco4 Kinase Domain bound to AppCp from D. discoideum.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein kinase roco4 | polymer | 287 | 32646.6 | 1 | UniProt (Q6XHB2) Pfam (PF07714) | Dictyostelium discoideum (Slime mold) | Ras of complex proteins and C-terminal of roc 4 |
| 2 | B (A) | PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | non-polymer | 505.2 | 1 | Chemie (ACP) | |||
| 3 | C (A) | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 209.2 | 1 | Chemie (BTB) | |||
| 4 | D (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | E (A) | water | water | 18.0 | 96 | Chemie (HOH) |
Sequence modifications
A: 1019 - 1292 (UniProt: Q6XHB2)
| PDB | External Database | Details |
|---|---|---|
| Gly 1006 | - | expression tag |
| Ala 1007 | - | expression tag |
| Met 1008 | - | expression tag |
| Gly 1009 | - | expression tag |
| Gly 1010 | - | expression tag |
| Ser 1011 | - | expression tag |
| Glu 1012 | - | expression tag |
| Phe 1013 | - | expression tag |
| Pro 1014 | - | expression tag |
| Lys 1015 | - | expression tag |
| Ser 1016 | - | expression tag |
| Arg 1017 | - | expression tag |
| Leu 1018 | - | expression tag |
| Ser 1179 | Gly 1179 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32646.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 738.8 | |
| All* | Total formula weight | 33385.3 |
