4F1M

Crystal Structure of the G1179S Roco4 Kinase Domain bound to AppCp from D. discoideum.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004672	molecular_function	protein kinase activity
A	0004713	molecular_function	protein tyrosine kinase activity
A	0005524	molecular_function	ATP binding
A	0006468	biological_process	protein phosphorylation

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	BINDING SITE FOR RESIDUE ACP A 1301

Chain	Residue
A	GLY1035
A	HOH1475
A	HOH1476
A	VAL1040
A	ALA1053
A	GLU1106
A	PHE1107
A	VAL1108
A	ARG1156
A	PHE1161
A	ASP1177

---

site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BTB A 1302

Chain	Residue
A	LYS1015
A	LYS1015
A	PHE1080

---

site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG A 1303

Chain	Residue
A	ASP1154
A	ASP1177
A	SER1179

---

Functional Information from PROSITE/UniProt

site_id	PS00107
Number of Residues	24
Details	PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. IGKGGFGLVHkGrlvkdksv..........VAIK

Chain	Residue	Details
A	ILE1032-LYS1055

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	266
Details	Domain: {"description":"Protein kinase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	9
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---