4EZ5
CDK6 (monomeric) in complex with inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cyclin-dependent kinase 6 | polymer | 307 | 35019.2 | 1 | UniProt (Q00534) Pfam (PF00069) | Homo sapiens (human) | Cell division protein kinase 6, Serine/threonine-protein kinase PLSTIRE |
| 2 | B (A) | {5-[4-(dimethylamino)piperidin-1-yl]-1H-imidazo[4,5-b]pyridin-2-yl}[2-(isoquinolin-4-yl)pyridin-4-yl]methanone | non-polymer | 477.6 | 1 | Chemie (0RS) |
Sequence modifications
A: 1 - 301 (UniProt: Q00534)
| PDB | External Database | Details |
|---|---|---|
| His 302 | - | expression tag |
| His 303 | - | expression tag |
| His 304 | - | expression tag |
| His 305 | - | expression tag |
| His 306 | - | expression tag |
| His 307 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 35019.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 477.6 | |
| All* | Total formula weight | 35496.8 |
