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4EYH

Human DNA polymerase iota incorporating dCTP opposite N-(deoxyguanosin-8-yl)-1-aminopyrene lesion

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(B)
DNA polymerase iotapolymer42047027.31UniProt (Q9UNA4)
Pfam (PF00817)
Pfam (PF21999)
Pfam (PF11799)
Homo sapiens (human)Eta2, RAD30 homolog B
2B
(T)
DNA templatepolymer82673.91
3C
(P)
DNA primerpolymer72107.41
4D
(B)
2'-DEOXYCYTIDINE-5'-TRIPHOSPHATEnon-polymer467.21Chemie (DCP)
5E, F, G
(B)
MAGNESIUM IONnon-polymer24.33Chemie (MG)
6H, I, J
(B, T, P)
waterwater18.028Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight51808.6
Non-Polymers*Number of molecules4
Total formula weight540.1
All*Total formula weight52348.7
*Water molecules are not included.

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PDB entries from 2025-09-24

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