4EXZ

Crystal Structure of the Q108K:K40L Mutant of Cellular Retinol Binding Protein Type II in Complex with All-trans-Retinal at 1.7 Angstrom Resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Retinol-binding protein 2	polymer	133	15581.5	2	UniProt (P50120) Pfam (PF00061)	Homo sapiens (human)	Cellular retinol-binding protein II, CRBP-II
2	C, E (A, B)	ACETATE ION	non-polymer		59.0	2	Chemie (ACT)
3	D, F (A, B)	RETINAL	non-polymer		284.4	2	Chemie (RET)
4	G, H (A, B)	water	water		18.0	164	Chemie (HOH)

Sequence modifications

A, B: 1 - 133 (UniProt: P50120)

PDB	External Database	Details
Leu 40	Lys 41	engineered mutation
Lys 108	Gln 109	engineered mutation
Asn 113	Asp 114	conflict

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	31163.0
Non-Polymers*	Number of molecules	4
	Total formula weight	687.0
All*	Total formula weight	31850.0

*Water molecules are not included.