4EXZ
Crystal Structure of the Q108K:K40L Mutant of Cellular Retinol Binding Protein Type II in Complex with All-trans-Retinal at 1.7 Angstrom Resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Retinol-binding protein 2 | polymer | 133 | 15581.5 | 2 | UniProt (P50120) Pfam (PF00061) | Homo sapiens (human) | Cellular retinol-binding protein II, CRBP-II |
| 2 | C, E (A, B) | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) PubChem (175) | |||
| 3 | D, F (A, B) | RETINAL | non-polymer | 284.4 | 2 | Chemie (RET) PubChem (1070) PubChem (23254473) PubChem (177675058) PubChem (638015) PubChem (5353924) PubChem (6436079) PubChem (6436082) PubChem (87082476) PubChem (87110449) PubChem (87110609) PubChem (88398773) PubChem (88407543) PubChem (11426127) PubChem (12227253) PubChem (12227254) PubChem (12227256) PubChem (12227257) PubChem (12227258) PubChem (12227259) PubChem (12227269) PubChem (12227270) PubChem (12227271) PubChem (5280490) PubChem (5381765) PubChem (134688327) PubChem (140510408) PubChem (145826762) PubChem (169423542) PubChem (172878320) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 164 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 133 (UniProt: P50120)
| PDB | External Database | Details |
|---|---|---|
| Leu 40 | Lys 41 | engineered mutation |
| Lys 108 | Gln 109 | engineered mutation |
| Asn 113 | Asp 114 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 31163.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 687.0 | |
| All* | Total formula weight | 31850.0 |
