4EXM
The crystal structure of an engineered phage lysin containing the binding domain of pesticin and the killing domain of T4-lysozyme
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Pesticin, Lysozyme Chimera | polymer | 347 | 39700.0 | 4 | UniProt (Q57159) UniProt (P00720) Pfam (PF21613) Pfam (PF00959) In PDB | Yersinia pestis | Endolysin, Lysis protein, Muramidase |
2 | water | water | 18.0 | 75 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 6 - 172 (UniProt: Q57159)
A, B, C, D: 173 - 334 (UniProt: P00720)
PDB | External Database | Details |
---|---|---|
Met -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
His -9 | - | expression tag |
His -8 | - | expression tag |
His -7 | - | expression tag |
His -6 | - | expression tag |
His -5 | - | expression tag |
His -4 | - | expression tag |
His -3 | - | expression tag |
His -2 | - | expression tag |
Glu -1 | - | expression tag |
Asn 0 | - | expression tag |
Leu 1 | - | expression tag |
Tyr 2 | - | expression tag |
Phe 3 | - | expression tag |
Gln 4 | - | expression tag |
Ser 5 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Arg 182 | Gly 13 | engineered mutation |
Thr 224 | Cys 55 | engineered mutation |
Ala 267 | Cys 98 | engineered mutation |
Ile 307 | Arg 138 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 158800.0 | |
All* | Total formula weight | 158800.0 |