4EW1

High resolution structure of human glycinamide ribonucleotide transformylase in apo form.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Trifunctional purine biosynthetic protein adenosine-3	polymer	209	22678.9	1	UniProt (P22102) Pfam (PF00551) In PDB	Homo sapiens (human)	Phosphoribosylamine--glycine ligase, Glycinamide ribonucleotide synthetase, GARS, Phosphoribosylglycinamide synthetase, Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase, Phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase, GAR transformylase, GART
2	A	PHOSPHATE ION	non-polymer		95.0	1	Chemie (PO4)
3	A	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)
4		water	water		18.0	227	Chemie (HOH)

Sequence modifications

A: 3 - 203 (UniProt: P22102)

PDB	External Database	Details
Ala 1	-	expression tag
Arg 2	-	expression tag
His 204	-	expression tag
His 205	-	expression tag
His 206	-	expression tag
His 207	-	expression tag
His 208	-	expression tag
His 209	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	22678.9
Non-Polymers*	Number of molecules	4
	Total formula weight	383.2
All*	Total formula weight	23062.1

*Water molecules are not included.